Rab22a sting
WebIntercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Cell ... PubMed ID: 36280710 DOI: 10.1038/s41422-022-00731-w. Luo X, Wang J, Lu J, Wang X, Miao Y, Li Q, Li X, Wang L. Rab22a Promotes Epithelial-Mesenchymal Transition in Papillary Thyroid Carcinoma by … WebMar 14, 2024 · Rab22a is a novel prognostic marker for cell progression in breast cancer. He M, Shen L, Jiang C, Gao G, Wang K, Jiao Y, Sun L, Cui Y, Ke Z, Yang ZHe M, et al. Int J Mol Med, 2024 Apr. PMID 32124943; Differential requirement of Rab22a for the recruitment of ER-derived proteins to phagosomes and endosomes in dendritic cells.
Rab22a sting
Did you know?
WebRAB22A. Ras-related protein Rab-22A is a protein that in humans is encoded by the RAB22A gene. [5] The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between ... WebIntercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Cell ... PubMed ID: 36280710 DOI: …
WebJan 2, 2024 · Importantly, these Rab22A-positive, STING-containing MVB-like structures can be observed in cells treated with STING agonists, indicating that they are not artifacts of … WebDec 18, 2024 · Notably, Rab22a-NeoF1 fusion protein could be stabilized in cells treated with proteasome inhibitor MG132 plus lysosome inhibitor BafA1. This indicated that Rab22a-NeoF1 fusion protein may be degraded by proteasome and/or lysosome, potentially providing an excellent opportunity to target this fusion protein by enhancing its degradation.
WebAug 24, 2024 · Kang et al. first confirmed that the chromosomal translocation-derived aberrant Rab22a was the driver for osteosarcoma lung metastasis in multiple … WebFeb 22, 2024 · 外泌体Rab22a- NeoF1融合蛋白可通过其供体细胞的结合伴侣PYK2激活RhoA来促进其阴性受体癌细胞的肺转移。因此，该外泌体Rab22a-NeoF1融合蛋白促进了其受体骨肉瘤细胞的肺转移，可以通过使用设计的RGD肽破坏其与PYK2的相互作用来靶向该过程，实现肺转移的抑制作用。
WebJun 4, 2004 · Rab22a Is Associated with the Recycling Endosome and Not the Incoming Clathrin-independent Endosome. The tubular endosomes containing MHCI also have Arf6 associated with them and have been implicated in the recycling of MHCI back to the PM (Radhakrishna and Donaldson, 1997; Caplan et al., 2002; Naslavsky et al., 2003).
WebOct 24, 2024 · STING V155M or STING R281Q levels in EVPs, but not their intracellular levels, could be increased by both RAB22A WT and RAB22A Q64L (Fig. 3f and … nujs official websiteWebOct 30, 2024 · 同时，rab22a 使 rab7 失活以抑制rafeesome 与溶酶体的融合，从而使带有活化 sting 的自噬体的内囊泡分泌成为一种新型的细胞外囊泡，我们将其定义为 r-ev（rab22a 诱导的细胞外囊泡）。活化的含有 sting 的 r-ev 诱导受体细胞向肿瘤微环境释放 ifnβ，从而促进 … nujs citation styleWebMar 1, 2024 · To determine whether Rab22a is involved in CSFV proliferation, we first examined the effect of Rab22a overexpression on virus replication. As shown in Fig. 2 A and C, the PK-15 cells transfected with exogenous Rab22a showed significantly increased levels of Rab22a compared with the control cells. The results of real-time PCR and … nujs law review citation styleWebDec 7, 2024 · Consistently, RAB22A enhances the antitumor effect of the STING agonist diABZI in mice, and a high RAB22A level predicts good survival in nasopharyngeal cancer … ninja professional 1100w blenderWebNational Center for Biotechnology Information nuk 0 2 months pacifier orthodonticWeb近日，相关论文以《RAB22A 介导的非典型自噬触发激活型 STING 的细胞间传递促进抗肿瘤免疫》（Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity）为题发表在 Cell Research 上，高瑛是第一作者，康铁邦和魏灯辉博士担任共同通讯作者 [1]。 nujs citation formatWebApr 2, 2024 · miR-204-5p acts as a tumor suppressor in colorectal cancer through inhibiting RAB22A and reveal RAB22A to be a new oncogene and prognostic factor for colorectal cancer. Exposure of human breast cancer cells to hypoxia augments microvesicle (MVs) shedding that is mediated by the HIF-dependent expression of the small GTPase RAB22A, … nujs journal of regulatory studies