Witryna10 kwi 2024 · The researchers have demonstrated that withaferin-loaded exosomes and paclitaxel-loaded exosomes have a lower IC 50 than those of the free drugs for anti-proliferative activities against A549 lung ... Witryna1 lut 2024 · The loaded exosomes are released by the diffusion-assisted process that control by the properties of the hydrogel network. Release profiles can be modulated by varying types of polymer, network crosslinking density, network morphology, mechanical behavior, and degradability of the hydrogel. Crosslinking density has significant …
Extracellular vesicles as drug vectors for precise cancer treatment ...
Witryna13 lut 2024 · In order to evaluate the loading efficiency of miR146a in SGM-miR146a-Exos, we detected the expression of miR146a in different exosomes especially the … WitrynaTriptolide has been proven to possess anticancer efficacy; however, its application in the clinical practice was limited by poor water solubility, hepatotoxicity, and nephrotoxicity. In this study, a triptolide-loaded exosomes delivery system (TP-Exos) was constructed and its effects on the proliferation and apoptosis of SKOV3 cells in vitro >and in vivo … flappers photos
Exosomes and mimics as novel delivery platform for cancer therapy
WitrynaWhen the TEM image was examined, spherical structures of approximately 52.34 and 116.1 nm for empty exosome and raloxifene loaded exosome were observed, respectively (Figs. 1C and ... Witryna1 lis 2024 · The amount of DOX loaded into exosomes was calculated from a standard curve obtained from BioTek ELX800 (Gene Company Limited, USA) by detecting the absorbance value at the wavelength of 490 nm. In order to measure the in-vitro drug release profile, 3 mL of Exo-Dox solution was transferred into dialysis tubes immersed … WitrynaOptimizing the loading technology of exosomes will reduce costs and improve productivity, which is an important factor for exosomes to enter the field of treatment. … flappers political rights